Aldosterone antagonists is the name given to a group of medicines.
Why has my doctor given me an aldosterone antagonist?
Aldosterone antagonists are used to treat heart failure. They are a type of diuretic (water tablets).
Check with your doctor if you are still not sure why you need an aldosterone antagonist.
How do they work?
Aldosterone antagonists prevent a substance in the body called “aldosterone” from working. Aldosterone makes the body retain water, therefore, by blocking its action, aldosterone antagonists cause the body to retain less water. This relieves ankle swelling and breathlessness.
You may find that you need to pass more water more often.
How should I take my aldosterone antagonist?
Always follow the instructions on the label. It is best to take these medicines earlier in the day to avoid needing to pass water during the night.
Do not stop taking this medicine unless your doctor tells you to stop.
What should I do if I miss a dose?
All drugs have side effects, but most people will not experience them. The following can occur in some people:
- diarrhoea or constipation
- nausea
- headache
- low blood pressure and dizziness
- in men, swelling or tenderness of the breast tissue can occur
Take it as soon as you remember. If it is nearly time for thenext dose, do not take the one you missed. Take the next dose at the usual time.
Do not double up the next dose.
Can I take other medicines while taking an aldosterone antagonist?
Yes, but some other medicines may a ect how they work. It is important that you check with your doctor or pharmacist before taking any other medicines including ones that you buy over the counter.
This information et is not intended as a substitute for any advice that your doctor, nurse or pharmacist may give you.
More detailed information can be obtained from the manufacturer’s information leafl et.
Pharmaceutical Service January 2021
Last Reviewed June 2025
Review Date June 2027