APPLIED-LUNG Study
If you are invited to attend a low dose CT scan as part of the NHS Lung Cancer Screening programme, you might also receive an invitation to take part in a research study called APPLIED-LUNG.
Why is this research being done?
To improve early diagnosis and survival from lung cancer, NHS Lung cancer screening with low dose computed tomography (CT) scans has been introduced. While CT scans can detect lung cancers, the widespread rollout of CT screening requires many resources and may not reach everyone who would benefit from Lung cancer screening.
Oxford Cancer Analytics (OXcan) have developed a blood test capable of detecting lung cancer by analysing proteins in the blood. The OXcan blood test has been shown to be effective in early studies.
OXcan is working with the Cheshire and Merseyside Lung cancer screening programme run by Liverpool Heart and Chest Hospital NHS Foundation Trust, and the University of Liverpool. We are asking 11,000 people undergoing a low dose CT scan as part of the NHS Lung cancer screening programme to participate in this study to see if the OXcan blood test can accurately identify people who do and do not need a CT scan.
It is entirely up to you whether you choose to take part. If you decide not to participate it will have no impact on the care you receive during your tests or treatment.
What will taking part involve?
If you agree to take part, a one-off research blood sample of up to 60 ml of blood (4 tablespoons) will be taken when you attend for your low dose CT scan. We may also ask you for a sputum, saliva, mouth swab and nose swab/scraping sample. We will also ask your permission to confidentially access your data.
You may be approached by the research team when you come in to see if you would be willing to take part in this research project. If you are willing to take part, you will be given a patient information leaflet and asked to sign a consent form.
If you do not wish to be approached, then please let the staff know when you attend for your scan or contact us using the details below.
Patient Information Video:
More details on APPLIED-LUNG can be found here: www.explainmytrial.com/applied-lung
If you'd like more information about APPLIED-LUNG, please contact the research team on 0151 600 1876 or email Research.LHCH@lhch.nhs.uk